PRDM16 REGULATES ARTERIAL DEVELOPMENT AND VASCULAR INTEGRITY

PRDM16 regulates arterial development and vascular integrity

Proper vascular formation is regulated by multiple signaling pathways.The vascular endothelial growth factor (VEGF) signaling promotes endothelial proliferation.Notch and its downstream targets act to lead endothelial cells toward an arterial fate through regulation of arterial gene expression.However, the White Willow Bark mechanisms of how endoth

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Targeted and reversible cancer cell-binding DNA nanoparticles

DNA nanoparticles (DeNAno) produced by rolling circle replication of circular oligonucleotide templates are a novel format Condensor Fan Motor for the selection of cell-binding reagents from randomized libraries.DeNAno particles consist of several hundred concatemers and can leverage that multivalency to bind to complex surfaces such as cells.In th

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